Arizona enters the final stretch of its season sitting at 4-3 overall and 1-3 in Big 12 conference play. The Wildcats need to win at least two of their final fi

One of Colorado football's best holds a school record for career yardage against the Arizona Wildcats. Here's how he did it.

Pick OU: Under (53.5) Arizona has covered the spread three times in six games. Arizona is unbeaten ATS (2-0) as a 4.5-point favorite or greater this season. Out of six Arizona games so far this season, three have gone over the total. Colorado's record against the spread in 2025 is 4-4-0.

Arizona is getting closer to kicking off its game against Colorado and looking to snap a 2-game losing streak.

Find single game tickets to the Arizona Wildcats vs. Colorado Buffaloes college football Week 10 matchup on Saturday, November 1, 2025 at Folsom Field.

Here is everything Colorado head coach Deion Sanders said in his weekly press conference before the Buffs' Big 12 matchup against Arizona.

Arizona boasts the seventh-ranked defense in the Big 12, holding opponents to minimal yardage by meeting them behind the line of scrimmage. It is Arizona's aggressive defense that has the Wildcats tied for 14th in the FBS in tackles for loss.