A new family of Ser-Thr kinases has been identified by the homology of their catalytic domain to the vaccinia virus B1R kinase (Nezu et al., 1997). Based on the latest information from the human ...
Overexpression of proto-oncogene c-jun and constitutive activation of the Jun N-terminal kinase (JNK) signaling pathway have been implicated in the leukemic transformation process. However, c-jun ...