Share New hifiasm-ONT assembly method delivers high-quality, cost-efficientnear T2T assemblies using standard Oxford Nanopore Simplex reads, broadening access to comprehensive genome assemblies ...

The mission to improve the widely used simplex-method algorithm showed instead why it works so well.

Compared with Levenberg Marquardt, the local and initial value sensitive algorithm, Simplex, a global algorithm, is the only robust and easy method which is irrelevant to initial input value.

New hifiasm-ONT assembly method delivers high-quality, cost-efficient near T2T assemblies using standard Oxford Nanopore Simplex reads, broadening access to comprehensive genome assemblies across ...

New Scientist takes a look at the simplex algorithm, now over 60 years old, which is used by everyone from fruit suppliers to banks to make decisions about non-linear problems with so many ...

OXFORD, England, April 18, 2025--A new paper, released this week on bioRxiv, introduces hifiasm-ONT, a breakthrough genome assembly algorithm that enables partially phased, near telomere-to-telomere ...