This systematic review investigates the high level of hypertension found among urban dwellers in West Africa and in the West African Diaspora in the Americas in relation to variants within the genes ...

Patients with sickle cell anemia (SCA) and persistent albuminuria (PA) exhibited significantly higher levels of urinary angiotensinogen (AGT). “What we’re most excited about is that urinary ...

Several of the genes encoding elements of the renin-angiotensinogen system, including angiotensinogen (AGT), subtype I of the angiotensin II receptor (AGTR1), angiotensin converting enzyme (ACE), and ...

The Multi-Ethnic Study of Atherosclerosis (MESA) is a longitudinal cohort study of African, Chinese and Hispanic Americans, as well as non-Hispanic Whites. Details about the study design have been ...

Urinary angiotensinogen levels at the time of hospital admission predicted acute decompensated heart failure patients' risk of developing acute kidney injury with considerable accuracy, scientists ...

Association between treatment facility volume and mortality in patients with glioblastoma (GBM): A large national analysis. This is an ASCO Meeting Abstract from the 2018 ASCO Annual Meeting I. This ...

Angiotensinogen plays a key role in hypertension pathogenesis. Zilebesiran, an RNA interference therapeutic agent that inhibits angiotensinogen production, is being studied for hypertension treatment.

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that it is broadening its pipeline with ALN-AGT, a subcutaneously ...

Increased expression of the Ang‐II (Angiotensin II) precursor AGT in aged astrocytes lead to increased Ang‐II signaling from aged astrocytes to endothelium, thus increasingblood–brain barrier (BBB) ...