Understanding the process of DNA repair, and, importantly, why it fails, holds huge importance as DNA damage is a key factor in many diseases. Critically, many cancer drugs, for example Cisplatin, ...
Newborn mice neurons can snap both DNA strands to migrate, then repair the breaks within a day. The process may be a normal part of brain development.
New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...
What If on MSN
Human DNA just stopped mutating. Here’s how it ends us
Your DNA is constantly changing. And if it weren’t for genetic mutations, evolution wouldn’t exist. So, what would life be ...
Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response. Whenever cells ...
Every time a cell copies its DNA, parts of the genome are exposed and vulnerable to damage or errors. Molecular biologist Simon Boulton is interested in how cells spot and repair damage to their DNA, ...
A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to discover that proteins present in the nuclear membrane of cells directly ...
When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells. If they stop functioning or there's not ...
The class of drugs known as DNA Damage Response inhibitors, which work by blocking cancer cells’ ability to repair their own damaged DNA, is expanding rapidly beyond its original anchor, the PARP ...
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