Bile salts play a crucial role in the digestion and absorption of dietary fats in the small intestine, particularly in the duodenum. The human bile salt export pump (BSEP), also known as ABCB11, ...

I am about to undergo gallbladder removal due to recurring pain from gallbladder sludge. Should I be taking replacements for the bile salts that I will no longer be able to produce, and if so, what is ...

(A) The classic bile acid synthesis pathway: cholesterol 7α-hydroxylase (CYP7A1) converts cholesterol to 7α-hydroxycholesterol (7α-HOC). The sterol 12α-hydroxylase (CYP8B1) converts the intermediate ...

Why are we asking for donations? Why are we asking for donations? This site is free thanks to our community of supporters. Voluntary donations from readers like you keep our news accessible for ...

In a major step toward a precision therapy for Clostridioides difficile (C. diff) infection, researchers at The Hospital for Sick Children (SickKids) have uncovered how the body's bile acids bind to ...

DEAR DR. ROACH: I’m a 67-year-old female in pretty good health. The only medications I take are for my thyroid, arthritis and hormone replacement. Early last year, I was sick with a cold/flu for a ...