mRNAs are protected at their 5′ ends by a cap structure consisting of an N7-methylated GTP molecule linked to the first transcribed nucleotide by a 5′–5′ triphosphate bond. The cap structure is ...
Most functional eukaryotic mRNAs contain a 5′ 7-methylguanosine (m 7 G) cap. Although capping is essential for many biological processes including mRNA processing, export and translation, the fate of ...