Computational chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

Type II topoisomerases are ubiquitous enzymes that play a pivotal role in modulating the topological configuration of double-stranded DNA. These topoisomerases are required for DNA metabolism and have ...

DNA repair systems have evolved to rectify exogenous or endogenous DNA lesions. FAN1 (FANCD2/FANCI associated nuclease 1) 1,2,3,4,5 is a DNA repair enzyme involved in removal of extrahelical ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

DNA aptamers are powerful molecular tools in biosensing, bioimaging and therapeutics. However, a limited understanding of their tertiary structures and binding mechanisms hinders their further ...

Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process.

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

James Dewey Watson, whose co-discovery of the twisted-ladder structure of DNA in 1953 helped launch a revolution in biology and medicine, died Thursday at age 97. He died in hospice care after a brief ...

Scientists uncovered DNA's double helix structure in 1953. James Watson and Francis Crick proposed the model. It explained ...