One of biology's fundamental questions is how our genes shape who we are. Adrian Serohijos and Stephen Michnick, professors ...

How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

McMillan’s lab aims to further characterize the role of SSB as a first responder and the proteins that are part of the crisis ...

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of ...

Sculpture of the DNA helix outside the Francis Crick Centre. Image by Tim Sandle. For more than half a century, protein crystallization has been one of the great bottlenecks of structural biology.

Generative AI is biology’s new playground. The technology powering popular chatbots can also dream up new, entirely novel versions of life’s most basic molecules, from DNA to proteins. Once the domain ...

Using DNA, the team directed proteins to assemble into diffraction-quality, intentionally designed crystal structures with atomic-level order. The strategy enabled the scientists to precisely control ...

Data from a new study in mice connects unrepaired DNA-protein crosslinks (DPCs), highly toxic tangles of protein and DNA, to inflammation-linked premature aging and embryonic lethality in mice. The ...

Some seeds refuse to die. Date palm seeds recovered from Herod’s Palace near Jerusalem, roughly 2,000 years old, have been ...

Two new federally funded studies offer detailed views of proteins repairing broken DNA inside tightly packed chromatin, and of the molecular toolkit they assemble at a break, with potential implicatio ...