Mechanotransduction—the process by which cells convert mechanical forces into biochemical signals—is now recognised as a fundamental regulator of embryonic morphogenesis. During early development, ...

Embryonic germ layers are the fundamental organizing principle in animal development. They provide the structural basis from which tissues and organs arise. During early embryogenesis, cells divide to ...

Research improves upon a popular experimental model of mammal development and in doing so, reveals more of the inner workings of a critical period during the formation of an embryo. Research from Ph.D ...

Chimpanzee naive pluripotent stem cells (PSCs) can now be grown in cellular cultures, reveals a recent study. They successfully created chimpanzee early embryo models, called 'blastoids,' and found ...

Embryonic development is one of the most dynamic biological processes in nature. Cells and tissues organize and reorganize ...

One of the biggest quests in biology is understanding how every cell in an animal’s body carries an identical genome yet still gives rise to a kaleidoscope of different cell types and tissues. A ...

For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...

Lymphoma invasion exhibited a germ layer-dependent organotropism, characterized by distinct heterogeneity in oncogenic mutations and signaling pathways, migration orderings, and developmental ...

Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...

Some newly reported clumps of cells growing in lab dishes have been hailed as the closest things to human embryos that scientists have ever made in the lab. These entities are human embryo models — ...