Researchers discovered that declining levels of phosphatidylcholine may be a major cause of age-related mitochondrial ...

The human genome is broadly classified into the genome residing in the cell nucleus (nuclear DNA) and the genome residing in the mitochondria (mitochondrial DNA: mtDNA). Mitochondria are cell ...

Discover C15 reports mitochondrial health is crucial for energy, aging, and disease, emphasizing its role in fatigue, burnout ...

Mitochondria rapidly accumulate mutations throughout a lifetime, potentially acting as a molecular clock for aging and disease. We profiled mitochondrial RNA across 47 human tissues from 838 ...

New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational levels coincide with later life and link to aging markers. Mitochondria are ...

New research profiles mitochondrial circular RNAs in Peripheral Blood Mononuclear Cells (PBMCs) from young and old human cohorts and probes how mitochondrial circRNAs and the mitochondrial RNA-binding ...

Mitochondria are the energy production centers in cells and have unique genetic information. Due to the irreplaceable function of mitochondria, mitochondrial dysfunction often leads to pathological ...

Cancer is fundamentally a disease of aging. As global populations grow older, the incidence of age-associated cancers, ...

The biology of burnout and what the geroscience literature says about one of the most studied molecules in longevity research. Running a company at scale is metabolically expensive. The 5 AM calls, ...

A new study reveals how paternal alcohol use before conception damages offspring mitochondria and accelerates aging.

Mutations accumulated in mitochondrial DNA associated with aging were earlier believed to cause aging by decreasing the energy-producing function (mitochondrial respiratory function). In this study, ...