The chemical origin of life on Earth is a puzzle that scientists have been trying to piece together for decades. Many hypotheses have been proposed to explain how life came to be and what chemical and ...

Fanfei Meng, Jianping Wang, Yanying He, Gregory M. Cresswell, Nadia A. Lanman, L. Tiffany Lyle, Timothy L. Ratliff, Yoon Yeo Proceedings of the National Academy of Sciences of the United States of ...

BOSTON — For treatment-naïve patients with e-antigen-negative hepatitis B, two nucleic acid polymers can markedly reduce viral DNA in the serum, according to preliminary trial results. In patients who ...

Scientists have been investigating properties of so-called xenonucleic acids or XNAs. They have demonstrated for the first time that six of these unnatural nucleic acid polymers are capable of sharing ...

Introducing therapeutic nucleic acids into cells is a way to potentially fix the genetic causes of diseases such as Down’s syndrome and cystic fibrosis. Scientists have designed synthetic materials to ...

Since the 1980s, researchers have pursued antisense nucleic acids as a way to reduce the expression of disease-causing genes. But delivering the sequences into a cell and protecting them from ...

University of Minnesota Twin Cities researchers in the Department of Chemistry have created a new polymer to deliver DNA and RNA-based therapies for diseases. For the first time in the industry, the ...

Whether one is elucidating biological mechanisms, correcting a faulty gene, or modulating gene expression, artificially introducing nucleic acids into cells requires an efficient and nontoxic delivery ...