The tubulin family of proteins are vital components of the eukaryotic cytoskeleton and are the main constituent of microtubules in living cells. The tubulin proteins α- and β polymerize into long ...

Researchers at Baylor College of Medicine have discovered a potential new strategy to fight back against Alzheimer’s and Parkinson’s diseases, conditions that are linked to the toxic accumulation of ...

The alternative text for this image may have been generated using AI. A comparison of the structure of tubulin heterodimers in T2R (which is similar to that of GDP–tubulin in curved protofilaments 11) ...

A structural protein best known for building the internal scaffolding of cells may double as a natural defense against the toxic protein clumps that drive Alzheimer’s and Parkinson’s diseases. New ...

A physical dimension of a cell is seldom its Achilles' heel. Yet for the neurons that are affected in most kinds of peripheral neuropathy, it is the length of their axons that best accounts for their ...

A phase 1/2 study evaluating the safety and efficacy of autologous TAC T cells in subjects with claudin 18.2+ advanced solid tumors. This is an ASCO Meeting Abstract from the 2025 ASCO ...

Though they share a hallmark neuropathology, α-synucleinopathies, including Parkinson’s disease, dementia with Lewy Bodies, and multiple system atrophy are a diverse group of disorders that are ...

Influence of CHAARTED, STAMPEDE, and LATITUDE eligibility criteria on utilization of abiraterone (A) and docetaxel (D). This is an ASCO Meeting Abstract from the 2018 Genitourinary Cancers Symposium.

Researchers from Sapienza University of Rome and affiliated organizations have detailed the discovery and preclinical evaluation of a series of antimitotic drugs as potential antilymphoma agents.