Expert Rev Clin Pharmacol. 2010;3(3):321-329. The cell's resting membrane potential at approximately -80 to -85 mV is maintained mainly by Kir2.1 channels during phase 4. Further ion channels, such as ...
Mathematicalmodels of cardiac action potentials have become increasingly important in the study of heart disease and pharmacology, but concerns linger over their robustness during long periods of ...
Pittsburgh, PA - Scientists have developed new voltage-sensitive dyes that allow them to view and record cardiac action potentials from layers deep within the heart [1]. These new dyes will allow ...
Jonathan R. Silva, Hua Pan, Dick Wu, Ali Nekouzadeh, Keith F. Decker, Jianmin Cui, Nathan A. Baker, David Sept, Yoram Rudy, Charles S. Peskin Proceedings of the ...
Mexiletine is a class IB antiarrhythmic drug used for the treatment of ventricular arrhythmias, specifically ventricular tachycardia and ventricular fibrillation. Mexiletine blocks cardiac sodium ...
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