Covalent chemical probes – chemical probes that form a covalent bond with their target biomacromolecule(s) represent powerful tools that can be used for biology discovery, target validation (or ...
In the battle against B-cell cancers, drugs that target the enzyme Bruton tyrosine kinase (BTK) have transformed treatment. Before the first BTK inhibitor, ibrutinib, came on the market in 2013, ...
Avalon BioVentures managing partners Sergio Duron and Sandy Madigan hadn’t even left their previous start-up when they hatched the idea for Enlaza Therapeutics. While they were both still at Nerio ...
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