The research team developed a genetically engineered mouse model carrying a mutation (E3896A) in RyR1, which disrupts its calcium-binding site, effectively disabling CICR while preserving ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

The research team developed a genetically engineered mouse model carrying a mutation (E3896A) in RyR1, which disrupts its calcium-binding site, effectively disabling CICR while preserving ...

Michael Gotthardt at the Max Delbrück Center and collaborators are developing a drug to treat a common type of heart failure ...

During the 1960s and 1970s, muscle cars were successful with the young car-buying demographic, not just with power and style, but also with cool model names. For the first few decades after cars ...

What Are Eccentric and Concentric Contractions? Eccentric contractions occur when a muscle lengthens under load, such as ...

An international research team has mapped the millisecond-by-millisecond process by which nerve signals activate muscles, uncovering a previously unseen “primed” intermediate step.

Merve Ceylan is a dietitian and health writer with four years of experience writing for companies in the nutrition and health industry. Nick Blackmer is a librarian, fact-checker, and researcher with ...

A BYD Seal U model car. Warren Buffett’s Berkshire Hathaway is no longer a shareholder in Chinese electric vehicle behemoth BYD, ending an investment that first started in 2008 and delivered billions ...

You may have heard that magnesium plays an important role in several bodily functions, including muscle contraction and regulating blood pressure and blood sugar. While it’s found in many foods, ...