Patrick Mahomes has made enough trips to Buffalo to know he and the Kansas City Chiefs shouldn't expect a warm welcome from Bills fans on Sunday.

The Kansas City Chiefs, led by quarterback Patrick Mahomes, face the Buffalo Bills, led by quarterback Josh Allen, on Sunday, Nov. 2, 2025 at Highmark Stadium in Erie County, New York.

A 36-34 Bills victory is the prediction from the Pittsburgh Post-Gazette’s Gerry Dulac. This is an excerpt from his story: “The Bills put up 40 points last week in Carolina; the Chiefs have won three ...

He always finds a way to come out on top vs Buffalo The Bills and Chiefs combined to score 25 points in the final 2 minutes ...

Josh Allen and the Buffalo Bills own Patrick Mahomes and the Kansas City Chiefs in the regular season. It’s been reversed when it matters most in the playoffs. The Bills ...

Pro Picks predicts Harrison Butker hits a game-winning field goal as time expires.