Oxidative decarboxylation of pyruvate to form acetyl–coenzyme A, a crucial step in many metabolic pathways, is carried out in most aerobic organisms by the multienzyme complex pyruvate dehydrogenase.
Wiskott–Aldrich Syndrome protein (WASP) is an important regulator of the actin cytoskeleton in haematopoietic cells. WASP-deficiency gives rise to the human disease Wiskott–Aldrich Syndrome (WAS), an ...
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