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1:02
Replying to @Lara ❤️ | Living with MCAS & Allergies | Mast Cell Activation Syndrome
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Dr. Michael Ruscio, DC, DNM
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When someone is in an MCAS flare, one of the first questions I ask is: what changed? Sometimes the answer is surprisingly small. You refill a medication you’ve taken for months, but the manufacturer changed—and suddenly the fillers, dyes, or inactive ingredients are slightly different. A medication you previously tolerated may now be contributing to symptoms. But this speaks to a bigger point: MCAS flares can give us clues in terms of what to avoid, but also, where to go with potential treatment
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Dr. Peter Kan
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People with MCAS can be reactive to far more than the active ingredient in a medication. Early on, I sometimes could not understand why certain patients seemed unable to tolerate almost any medication—or why they developed side effects that did not fit with what the medication actually does. Then I realized that a pill is rarely just the medication itself. Many tablets and capsules contain seven or eight inactive ingredients, including fillers, binders, dyes, coatings, and preservatives. Each on
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One of the more characteristic complaints I hear during an MCAS flare is “internal vibrating.” Patients often describe feeling completely still on the outside, while on the inside it feels like their entire body is buzzing, humming, trembling, or vibrating. I hear this surprisingly often in patients with active mast cell symptoms. It’s not specific enough to diagnose MCAS by itself—and internal tremor can occur in other neurologic or autonomic conditions—but when it appears alongside a patient’s
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