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Mechanism of action of opioids
Opioid agonists produce analgesia by binding to G protein-coupled receptors (GPCRs) in the brain and spinal cord regions involved in the transmission and modulation of pain Opioid drugs mimic endogenous compounds: endorphins, enkephalins, and dynorphins that bind to opioid receptors. Four opioid receptor types: mu (μ), kappa (κ), delta (δ ...
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Brendan Ruh on Instagram: "The opioid effects of gluten are actually pretty wild. If your gut does well with gluten I’m not saying you need to never have it. It can be tasty and I’ll sometimes have some sourdough or if the occasion presents itself some pizza or pasta. I just don’t eat it often AT ALL because if I eat if often I feel a bit sluggish and eh not great I know I feel this way because I’ve experimented around with not having it for a while, reintroducing it, and that way I know how I f
Brendan Ruh on Instagram: "The opioid effects of gluten are actually pretty wild. If your gut does well with gluten I’m not saying you need to never have it. It can be tasty and I’ll sometimes have some sourdough or if the occasion presents itself some pizza or pasta. I just don’t eat it often AT ALL because if I eat if often I feel a bit sluggish and eh not great I know I feel this way because I’ve experimented around with not having it for a while, reintroducing it, and that way I know how I f
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