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Patients with COPD frequently have an elevated hemoglobin level. Dehydration plays a small role in this elevation. While it is only a small role, it is an important reminder to consider IV fluids when a patient arrives in a COPD exacerbation. Chronic hypoxemia signals the kidneys to produce more erythropoietin (EPO). EPO signals the bone to increase RBC production. More RBCs in the circulation increase oxygen carrying capacity in the blood. Even in the presence of hypoxemia. Finally, patients wi
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