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What causes hives? When your body is exposed to something, either through breathing it in or eating or drinking it, or having it touch your skin, there are cells called mast cells. These cells release histamine, and that histamine causes your skin to cause hives, essentially welts. And what happens is histamine causes your blood vessels to go from being small to being big, in that sense, blood to the area, and cause the swelling. Now, if the hives are really bad, you can try something like Zyrte
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